Biochemical outcomes by allocation
| Active (2 months: n=131; 12 months: n=118) | Control (2 months: n=97; 12 months: n=86) | Adjusted mean difference (95% CI)* | p for allocation-time interaction | p for individual time point† | |
|---|---|---|---|---|---|
| Mean trough serum 25(OH)D, nmol/L (SD) | |||||
| 2 months | 65.5 (19.8) | 52.9 (21.7) | 13.2 (8.3 to 18.0) | <0.001 | <0.001 |
| 12 months | 85.3 (24.3) | 59.1 (26.0) | 25.7 (20.6 to 30.7) | <0.001 | |
| Mean serum corrected calcium, mmol/L (SD) | |||||
| 2 months | 2.40 (0.09) | 2.40 (0.09) | 0.00 (–0.02 to 0.02) | 0.21 | – |
| 12 months | 2.43 (0.13) | 2.41 (0.07) | 0.02 (0.00 to 0.04) | – | |
*Adjusted for study group (resident vs carer) and minimisation variables (level of care, size of scheme and season of randomisation).
†p for individual time point only presented where p for allocation-time interaction <0.05.
25(OH)D, 25-hydroxyvitamin D.