Table 4

List of 30 statistically significant gene ontology (GO) terms implicated by differential expression of genes in day 3 epithelial (type II like) cells treated with vitamin D3 100 nM relative to untreated cells

GOAnnotated genesTotalp Value
Immune response48760.00000
Immune system process581030.00000
Cytokine activity25360.00001
Extracellular process45860.00003
Signal transducer activity751730.00008
Molecular transducer activity751730.00008
Plasma membrane1333560.00013
DNA replication20290.00015
Receptor activity571240.00015
Defence response42830.00015
Monoxygenase activity12130.00018
ATPase activity, coupled to transmembrane movement of substances6107(0.00018)
Primary active transmembrane transporter activity6107(0.00018)
Hydrolase activity, acting on acid anhydrides, catalysing transmembrane movement of substances6107(0.00018)
P-P-bond-hydrolysis-driven transmembrane transporter activity6107(0.00018)
ATPase activity, coupled to movement of substances6107(0.00018)
Cell surface receptor linked signal transduction691620.00025
Response to external stimulus501080.00030
Response to wounding38760.00043
Heme binding12140.00060
Tetrapyrrole binding12140.00060
Cellular biosynthetic process15145(0.00105)
Biosynthetic process29214(0.00121)
Extracellular region part581370.00168
Nucleotide biosynthetic process161(0.00168)
Cell cycle process44970.00208
Nucleobase-containing small molecule metabolic process369(0.00412)
Nucleotide metabolic process368(0.00466)
  • p values of underrepresented GO terms are denoted in parentheses.