TableĀ 4

Prediction rule test characteristics for 7-day PE-related complications in 496 normotensive patients with acute symptomatic PE

sPESI
variable
Lactate
variable
Troponin
variable
TTE
variable
sPESI plus lactate variableTroponin plus TTE
variable
Troponin plus TTE plus lactate
variable
Positive test, N (%)361 (72.7)135 (27.2)117 (23.6)201 (40.5)108 (21.7)70 (14.1)28 (5.6)
Sensitivity, %85.0 (61.7 to 96.0)70.0 (46.2 to 87.0)35.0 (16.5 to 58.5)70.0 (46.1 to 87.1)60.0 (36.9 to 79.7)30.0 (13.0 to 53.4)25.0 (9.9 to 46.8)
Specificity, %27.7 (26.8 to 28.2)74.6 (73.6 to 75.3)76.9 (76.1 to 77.9)60.7 (59.7 to 61.4)79.8 (78.9 to 80.7)86.6 (85.8 to 87.5)95.2 (94.5 to 96.1)
Positive predictive value, %4.7 (3.4 to 5.3)10.4 (5.8 to 16.8)6.0 (2.8 to 10.0)7.0 (4.6 to 8.7)11.1 (7.0 to 13.9)8.6 (3.7 to 15.3)17.9 (6.1 to 36.9)
Negative predictive value, %97.8 (94.3 to 99.4)98.3 (97.0 to 99.3)96.6 (95.6 to 97.8)98 (96.3 to 99.1)97.9 (96.7 to 99.0)96.7 (95.9 to 97.8)96.8 (96.1 to 97.7)
Positive likelihood ratio1.18 (0.84 to 1.33)2.75 (1.75 to 3.52)1.51 (0.69 to 2.64)1.78 (1.15 to 2.26)2.98 (1.75 to 4.12)2.23 (0.92 to 4.28)5.17 (1.81 to 11.97)
Negative likelihood ratio0.54 (0.44 to 1.43)0.40 (0.17 to 0.73)0.85 (0.53 to 1.10)0.49 (0.21 to 0.90)0.50 (0.25 to 0.80)0.81 (0.53 to 1.01)0.79 (0.55 to 0.95)
  • Unless otherwise indicated, values in parentheses are 95% CI.

  • sPESI, simplified PE Severity Index; TTE, transthoracic echocardiography.