Baseline characteristics and chest CT findings for subjects in the subcohort (n=704) and for the COPD cases (n=338)
| Characteristic or finding | Subcohort | COPD cases | p Value* |
|---|---|---|---|
| Age (years) | 62 (54–72) | 71 (61–76) | <0.001 |
| Male gender | 419 (60) | 184 (54) | 0.143 |
| CT indication | <0.001 | ||
| Cardiovascular disease | 310 (44) | 200 (59) | |
| Trauma | 38 (5) | 11 (3) | |
| Haematological malignancy | 136 (19) | 35 (10) | |
| Mediastinal disease | 128 (18) | 62 (18) | |
| Other | 92 (13) | 30 (9) | |
| Emphysema (range sum score 0–20) | <0.001 | ||
| Mild (sum score 1–3) | 147 (21) | 58 (17) | |
| Moderate (sum score 4–6) | 48 (7) | 27 (8) | |
| Severe (sum score ≥7) | 72 (10) | 105 (31) | |
| Airway thickening (range sum score 0–5) | <0.001 | ||
| Mild (sum score 1) | 91 (13) | 57 (17) | |
| Moderate (sum score 2) | 56 (8) | 63 (19) | |
| Severe (sum score ≥3) | 32 (5) | 45 (13) | |
| Bronchiectasis (range sum score 0–5) | 0.068 | ||
| Mild (sum score 1) | 90 (13) | 49 (14) | |
| Moderate (sum score 2) | 37 (5) | 29 (9) | |
| Severe (sum score ≥3) | 51 (7) | 32 (9) |
Categorical variables are expressed as number (%). Continuous variables are expressed as median (IQR).
*Continuous and categorical variables were compared between the subjects in the subcohort and cancer cases using the Mann–Whitney U test and χ2 analysis.