Case series of CT-guided biopsy of pulmonary nodules
| Total no cases | Follow-up data available | Useful sample obtained | True +ve | True −ve | False +ve | False −ve | Sensi-tivity (%) | Speci-ficity (%) | Negative LR | |
|---|---|---|---|---|---|---|---|---|---|---|
| Baldwin et al189 | 114 | 114 | 98 | 71 | 23 | 1 | 3 | 96 | 96 | 0.042 |
| Gupta et al190 | 176 | 176 | 143* | 104 | 34 | 0 | 5 | 95 | 100 | 0.046 |
| Hayashi et al191 | 52 | 52 | 50 | 34 | 15 | 0 | 1 | 97 | 100 | 0.029 |
| Jin et al192 | 71 | 61 | 61 | 35 | 25 | 0 | 1 | 97 | 100 | 0.028 |
| Ohno et al193 | 396 | 396 | 396 | 266 | 80 | 20 | 30 | 90 | 72 | 0.141 |
| Romano et al194 | 229 | 184 | 184 | 113 | 56 | 0 | 15 | 88 | 100 | 0.117 |
| Santambrogio et al195 | 220 | 220 | 207 | 130 | 68 | 1 | 8 | 94 | 99 | 0.059 |
| Tsukada et al196 | 138† | 138 | 138 | 70 | 44 | 3 | 21 | 77 | 94 | 0.245 |
| Wagnetz et al197 | 108 | 104 | 104 | 79 | 16‡ | 0 | 9 | 90 | 100 | 0.102 |
| Westcott et al198 | 64 | 64 | 64 | 40 | 21 | 0 | 3 | 93 | 100 | 0.070 |
| Total | 1568 | 1509 | 1445 | 942 | 382 | 25 | 96 | 91 | 94 | 0.10 (95% CI 0.08 to 0.12) |
*155 cases reported in paper, but data only presented for 143 cases.
†Includes results from repeat biopsies of same nodules.
‡Calculated from information provided in text.
LR, likelihood ratio.