Table 2.

Analysis of primary outcome and secondary outcomes measured at 6 months.

Primary care (n=101) Mean (95% CI)Sleep unit (n=109) Mean (95% CI)Difference in mean change Mean (95% CI)P valueBMI-adjusted p valueAntihypertensive drugs-adjusted P value
Primary outcome
 CPAP compliance (hours/night)4.94 (4.47 to 5.50)5.23 (4.79 to 5.66)−0.29 (−0.85)*0.180.15
Secondary outcomes
Epworth Sleep Scale Score
 Baseline10.50 (9.37 to 11.62)10.55 (9.46 to 11.64)
 6-months5.92 (5.04 to 6.80)4.18 (3.26 to 5.10)
 Change−4.58 (−5.79 to −3.36)§−6.37 (−7.55 to −5.19)§1.79 (0.05 to 3.53)0.040.049
Patient satisfaction at 6 months7.54 (7.01 to 8.08)9.03 (8.50 to 9.56)−1.49 (−2.22 to −0.76)<0.001<0.001
EQ-5D 
 Baseline0.77 (0.73 to 0.81)0.79 (0.75 to 0.83)
 6-months0.81 (0.77 to 0.86)0.86 (0.82 to 0.90)
 Change0.04 (−0.01 to 0.08)0.07 (0.03 to 0.11)§−0.03 (−0.09 to 0.02)0.250.33
Body mass index (kg/m2)
 Baseline32.53 (31.19 to 33.86)34.57 (33.28 to 35.85)
 6-months33.06 (31.70 to 34.42)34.53 (33.23 to 35.84)
 Change0.54 (0.12 to 0.95)§−0.03 (−0.42 to 0.36)0.57 (0.01 to 1.13)0.04-
Systolic blood pressure (mm Hg)
 Baseline135.06 (131.14 to 138.99)134.57 (131.06 to 138.08)
 6-months131.29 (127.40 to 135.17)136.11 (132.66 to 139.56)
 Change−3.78 (−8.62 to 1.07)1.54 (−1.93 to 5.01)−5.32 (−10.91 to 0.28)0.060.070.14
Diastolic blood pressure (mm Hg)
 Baseline81.26 (78.75 to 83.77)84.36 (82.11 to 86.61)
 6-months79.54 (76.96 to 82.12)85.00 (82.49 to 87.51)
 Change−1.72 (−4.91 to 1.46)0.64 (−2.08 to 3.36)−2.36 (−6.13 to 1.41)0.210.220.38
  • Change computed as the difference of the 6-months values with respect to the baseline values.

  • Difference in mean change computed as the difference of Primary Care with respect to Sleep Unit values.

  • BMI; Body Mass Index, EQ; EuroQol. *Mean (one-sided 95% CI, lower bound).

  • †One-sided p-values.

  • ‡Patient satisfaction visual scale (range from 0 to 10). §P<0.001 for paired comparison of outcome measures examining change from baseline to 6 months.

  • The statistically significant p values (p values lower than 0.05) are bolded.