Predictive performance of independent indicators
| Outcomes | Predictors | Cut-off value | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | LR+ | LR− |
|---|---|---|---|---|---|---|---|---|
| Mortality | Lactate (mmol/L) | 4 | 68 | 82 | 65 | 83 | 3.7 | 0.4 |
| CURB-65 | 2 | 57 | 73 | 51 | 77 | 2.1 | 0.6 | |
| Hospitalisation | Lactate (mmol/L) | 3 | 68 | 82 | 80 | 70 | 3.7 | 0.4 |
| CURB-65 | 1 | 79 | 40 | 59 | 64 | 1.3 | 0.5 | |
| ICU admission | Lactate (mmol/L) | 6 | 81 | 92 | 63 | 96 | 9.7 | 0.2 |
| CURB-65 | 3 | 33 | 90 | 36 | 88 | 3.3 | 0.8 |
ICU, intensive care unit; LR−, negative likelihood ratio; LR+, positive likelihood ratio; NPV, negative predictive value; PPV, positive predictive value.