Individuals where lung function was measured at all ages except 6 years (n=91 unless stated) | Individuals where lung function was measured on more than three occasions (n=162 unless stated) | Whole cohort (n=253 unless stated) | |
---|---|---|---|
Percentage of male (n) | 59% (54) | 56% (91) | 56% (142) |
Percentage with maternal history of asthma (n) | 22% (20) | 18% (29) | 20% (51) |
Percentage with paternal history of asthma (n) | 11% (10) | 14% (22) | 15% (35/242) |
Percentage with mothers who smoked during pregnancy (n) | 25% (23) | 28% (45) | 32% (80/252) |
Percentage with atopy during infancy (n) | 13% (12) | 17% (28)* | 13% (32/153) |
Percentage with flow limitation at 1 month of age (n) | 2% (2)* | 10% (16) | 10% (23/243) |
Mean %V'maxFRC at 1 month (SD) | 110 (52)* | 100 (48) n=155 | 99 (48) n=241 |
Mean %V'maxFRC at 6 months (SD) | 107 (48) | 104 (44) n=150 | 104 (46) n=192 |
Mean %V'maxFRC at 12 months (SD) | 95 (42) | 98 (39) n=138 | 98 (39) n=164 |
Mean % FEF25–75 at 6 years (SD) | 90 (24)* | 87 (24) n=96* | 85 (24) n=106 |
Mean % FEF25–75 at 12 years (SD) | 101 (20) | 99 (20) n=156 | 99 (20) n=183 |
Mean % FEF25–75 at 18 years (SD) | 107 (24) | 107 (23) n=129 | 107 (23) n=141 |
Percentage of current smoker at 18 | 21% (19) | 23% (30) | 22% (33/148) |
Percentage with asthma ever by 18 years | 39% (31)* | 46% (67) | 46% (80/172) |
*p<0.05 compared to the whole cohort.