Mean difference in FEV1 between treatment groups for the intention-to-treat (ITT, n=46), ‘as treated’ (n=46) and Completer (n=33) populations
| Outcome FEV1 (L) | Mean difference in FEV1 (azithromycin minus placebo) | 95% CI for population mean difference | p Value |
|---|---|---|---|
| ITT analysis 46 patients, 177 measurements | |||
| Mean difference in FEV1 between treatment arms, adjusted for baseline FEV1, randomisation stratification variables (disease and transplant) and time since randomisation | 0.035 | −0.112 to 0.182 | 0.6 |
| ‘As treated’ analysis 46 patients, 177 measurements | |||
| Mean difference in FEV1 between treatment arms, adjusted for baseline FEV1, randomisation stratification variables (disease and transplant) and time since randomisation | 0.306 | 0.181 to 0.431 | <0.001 |
| Completers analysis 33 patients, 124 measurements | |||
| Mean difference in FEV1 between treatment arms, adjusted for baseline FEV1, randomisation stratification variables (disease and transplant) and time since randomisation | 0.278 | 0.170 to 0.386 | <0.001 |