Table 2

Correlations between blood biomarkers, lung function and survival among patients with idiopathic pulmonary fibrosis

VariableBy variablerSp Value
MMP3FVC % predicted−0.250.03
DLCO, % predicted−0.140.3
Dyspnoea Score0.240.04
Survival time−0.330.004
CXCL130.37<0.001
CXCL13FVC % predicted−0.010.9
DLCO, % predicted−0.320.007
Dyspnoea Score0.40<0.001
Survival time−0.240.03
Survival (Cox proportional hazards model)Coefficient
(95% CI)
p Value
MMP31.018
(1.010–1.024)
5.0×10−8
CXCL131.003
(1.002–1.005)
7.3×10−6
  • Italics denote nominal statistical significance (p-value <0.05). DLCO, diffusing capacity of carbon monoxide; rS, Spearman's rank-order correlation coefficient.