Crude incidence rates and adjusted incidence rate ratios (IRRs) of lung cancer and COPD as a function of 100 µmol/L (1.68 mg/dL) serum uric acid levels stratified on smoking status
| Events/PYs per 10 000 | Crude incidence rate (95% CI) | Adjusted IRRs* (95% CI) per 100 µmol/L increase in uric acid | |
|---|---|---|---|
| Lung cancer | |||
| Non-smoker | 112/43.7 | 2.6 (2.1 to 3.1) | 1.04 (0.85 to 1.26) |
| Ex-smoker | 531/35.4 | 15.0 (13.8 to 16.3) | 1.04 (0.96 to 1.14) |
| Light-moderate | 226/8.9 | 25.4 (22.3 to 29.0) | 0.91 (0.78 to 1.05) |
| Heavy | 146/4.5 | 32.2 (27.3 to 37.8) | 0.72 (0.59 to 0.87) |
| COPD | |||
| Non-smoker | 643/41.1 | 15.7 (14.5 to 16.9) | 1.03 (0.94 to 1.12) |
| Ex-smoker | 1894/31.2 | 60.7 (58.0 to 63.5) | 1.03 (0.99 to 1.08) |
| Light-moderate | 822/7.6 | 108 (101 to 116) | 0.88 (0.81 to 0.95) |
| Heavy | 542/3.9 | 140 (129 to 153) | 0.91 (0.83 to 1.00) |
Wald tests were used to calculate p values for categorical variables and interaction terms.
*Adjusted for age, sex, social deprivation, year of uric acid test, alcohol, height, weight, blood pressure, non-European ethnicity and particle pollution.
PYs, person years.