No. of patients (%) | No. of patients with surgery (%) | Unadjusted OR (95% CI) | Adjusted OR (95% CI)* | χ2 p value for trends | |
---|---|---|---|---|---|
Sex | |||||
Female | 41 744 (43.57) | 5833 (13.97) | 1 | 1 | |
Male | 54 074 (56.43) | 6926 (12.81) | 0.90 (0.87 to 0.93) | 0.94 (0.89 to 0.98) | 0.018† |
Age | |||||
<54 | 5937 (6.20) | 1049 (17.67) | 1 | 1 | |
55–59 | 6282 (6.56) | 1134 (18.05) | 1.02 (0.93 to 1.12) | 1.01 (0.89 to 1.14) | |
60–64 | 11 220 (11.71) | 2066 (18.41) | 1.05 (0.96 to 1.14) | 0.91 (0.81 to 1.01) | |
65–69 | 14 179 (14.80) | 2614 (18.44) | 1.05 (0.97 to 1.13) | 0.92 (0.83 to 1.02) | |
70–74 | 16 560 (17.28) | 2689 (16.24) | 0.90 (0.83 to 0.97) | 0.77 (0.69 to 0.85) | |
75–79 | 16 806 (17.54) | 2082 (12.39) | 0.65 (0.60 to 0.71) | 0.55 (0.49 to 0.61) | |
80–84 | 14 073 (14.69) | 940 (6.68) | 0.33 (0.30 to 0.36) | 0.25 (0.22 to 0.28) | |
85+ | 10 761 (11.23) | 185 (1.72) | 0.08 (0.06 to 0.09) | 0.06 (0.05 to 0.08) | <0.001 |
Stage | |||||
IA–IB | 11 284 (11.78) | 6189 (54.85) | 1 | 1 | |
IIA–IIB | 5686 (5.93) | 2392 (42.07) | 0.59 (0.56 to 0.63) | 0.54 (0.50 to 0.58) | |
IIIA | 9249 (9.65) | 1448 (15.66) | 0.15 (0.14 to 0.16) | 0.10 (0.09 to 0.11) | |
IIIB | 11 697 (12.21) | 474 (4.05) | 0.03 (0.03 to 0.04) | 0.02 (0.02 to 0.03) | |
IV | 39 505 (41.23) | 599 (1.52) | 0.01 (0.01 to 0.02) | 0.01 (0.01 to 0.01) | <0.001 |
Missing | 18 397 (19.20) | 1657 (9.01) | 0.08 (0.07 to 0.08) | 0.07 (0.07 to 0.08) | |
Performance status | |||||
0 | 15 357 (16.03) | 5245 (34.15) | 1 | 1 | |
1 | 24 945 (26.03) | 4461 (17.88) | 0.41 (0.40 to 0.43) | 0.49 (0.46 to 0.52) | |
2 | 16 368 (17.08) | 769 (4.70) | 0.09 (0.08 to 0.10) | 0.12 (0.11 to 0.14) | |
3 | 15 377 (16.05) | 138 (0.90) | 0.01 (0.01 to 0.02) | 0.03 (0.02 to 0.03) | |
4 | 5168 (5.39) | 16 (0.31) | 0.01 (0.01 to 0.01) | 0.02 (0.01 to 0.03) | <0.001 |
Missing | 18 603 (19.41) | 2130 (11.45) | 0.24 (0.23 to 0.26) | 0.36 (0.34 to 0.39) | |
Ethnicity | |||||
Caucasian | 60 396 (63.03) | 8173 (13.53) | 1 | 1 | |
Black patients | 683 (0.71) | 98 (14.35) | 1.07 (0.86 to 1.32) | 1.15 (0.86 to 1.53) | |
Asian | 827 (0.86) | 120 (14.51) | 1.08 (0.89 to 1.31) | 1.10 (0.85 to 1.43) | |
Mixed | 107 (0.11) | 17 (15.89) | 1.20 (0.71 to 2.02) | 0.97 (0.48 to 1.94) | |
Others | 737 (0.77) | 100 (13.57) | 1.00 (0.81 to 1.24) | 1.15 (0.87 to 1.53) | |
Missing | 33 068 (34.51) | 4251 (12.86) | 0.94 (0.90 to 0.98) | 0.93 (0.89 to 0.99) | 0.435† |
Townsend quintile | |||||
1 (most affluent) | 14 975 (15.63) | 2158 (14.41) | 1 | 1 | |
2 | 17 837 (18.62) | 2444 (13.70) | 0.94 (0.88 to 1.00) | 0.89 (0.82 to 0.97) | |
3 | 18 839 (19.66) | 2492 (13.23) | 0.90 (0.85 to 0.96) | 0.84 (0.78 to 0.92) | |
4 | 20 332 (21.22) | 2645 (13.01) | 0.88 (0.83 to 0.94) | 0.83 (0.76 to 0.90) | |
5 | 21 966 (22.92) | 2935 (13.36) | 0.91 (0.86 to 0.97) | 0.80 (0.74 to 0.87) | <0.001 |
Missing | 1869 (1.95) | 85 (4.55) | 0.28 (0.22 to 0.35) | 0.44 (0.34 to 0.58) | |
Charlson Index | |||||
0 | 29 509 (30.80) | 4830 (16.37) | 1 | 1 | |
1 | 19 001 (19.83) | 3292 (17.33) | 1.07 (1.01 to 1.12) | 1.01 (0.95 to 1.08) | |
2–3 | 17 418 (18.18) | 2721 (15.62) | 0.94 (0.89 to 0.99) | 0.99 (0.95 to 1.06) | |
4+ | 29 890 (31.19) | 1916 (6.41) | 0.34 (0.33 to 0.36) | 0.78 (0.73 to 0.84) | 0.003 |
Source of referral | |||||
Referral from GP | 45 465 (47.45) | 7167 (15.76) | 1 | 1 | |
Emergency adm. | 11 991 (12.51) | 480 (4.00) | 0.22 (0.20 to 0.24) | 0.54 (0.48 to 0.60) | |
Ref. from consultant | 20 137 (21.02) | 3295 (16.36) | 1.04 (0.99 to 1.09) | 1.12 (1.05 to 1.19) | |
Other sources | 16 115 (16.82) | 1564 (9.71) | 0.57 (0.54 to 0.60) | 0.87 (0.81 to 0.94) | <0.001† |
Missing | 2110 (2.20) | 253 (11.99) | 0.72 (0.63 to 0.83) | 0.85 (0.72 to 1.01) |
*Odd ratio adjusted for every other variable in the table.†Log likelihood ratio test.
GP, general practioner.