Baseline characteristics of intention-to-treat population
| Variable at screening/baseline (intention-to-treat population) | Inhaled mannitol n=233 | Control n=228 |
|---|---|---|
| Age years | 59±14 | 60±13 |
| Female sex (%) | 63.1 | 62.3 |
| Caucasian (%) | 94.8 | 96.5 |
| FEV1 | ||
| Litres | 1.76±0.59 | 1.67±0.51 |
| % Predicted | 63.0±13.6 | 61.5±13.4 |
| FEV1/FVC ratio (%) | 65±11 | 65±11 |
| Ex-smoker (%) | 39.9 | 38.6 |
| Exacerbation rate (events/year) | 3.20±1.4 | 3.25±1.4 |
| 24 h sputum weight (g) | 28.9±18.7 | 29.0±19.9 |
| SGRQ total score | 53.0±14.6 | 52.2±14.7 |
| Macrolide use (%) | 20.2 | 24.6 |
| Pseudomonas aeruginosa positive (%) | 17.7 | 20.6 |
| Cause of bronchiectasis (%) | ||
| Unknown | 50.6 | 50.0 |
| Infection | 32.2 | 36.0 |
| Primary ciliary dyskinesia | 4.3 | 2.2 |
| Other | 12.9 | 11.8 |
Plus-minus values are means ±SD.
SGRQ, St George's Respiratory Questionnaire.