Table 2

Diagnosis and treatment of recognised comorbidities in severe asthma

Comorbid conditionTestTreatment
Gastro-oesophageal reflux3 months empirical therapy trial with proton pump inhibitors or oesophageal pH testingLifestyle modifications
Proton pump inhibitors
Obesity with or without obstructive sleep apnoea syndromePolysomnographyWeight control
Positive airway pressure
Oral appliances
Sinus diseaseCT scanNasal irrigation with saline
NasendocopyCorticosteroid spray
Corticosteroid drops
Depression/anxietyEvaluation by mental health professionalMedical treatment or psychotherapy by mental health professional