Demographic and clinical characteristics of the patients with tracheal carcinoma in situ included in the study
| Patient | Sex | Smoking (pack years) | Initial malignancy (stage)* | Site | Age (surgery) | Site(s) of new tumour (histology/time to diagnosis†) | Sites tested | Specimens analysed |
|---|---|---|---|---|---|---|---|---|
| 1 | M | 60 | SqCC (T1N0M0) | LUL | 58 | Left completion pneumonectomy (SqCC) arising from a region of LUL stump (M93) | 19 | 46 |
| 2 | M | 30–40 | SqCC (T1N0M0) | LLL | 72 | LLL stump (SqCC/M48) | 6 | 8 |
| Right Lung (SqCC/M50) | ||||||||
| LUL (CIS /M78) | ||||||||
| Trachea (SD /M85) | ||||||||
| 3 | M | 47 | SqCC (T1N0M0) | LUL | 66 | Lower Trachea/LMB stump (both early invasive SqCC/M42) | 5 | 6 |
| 4 | M | 40 | SqCC (T2N0M0) | RUL | 57 | RUL stump (SqCC/M11) Trachea posterior wall (invasive SqCC/M11) | 3 | 3 |
| 5 | M | 40 | SqCC (T1N0) | RML RLL | 70 | RIB (CIS /M60) | 6 | 7 |
*Refers to initial malignancy detected prior to patient's referral to UCLH.
†Refers to the time interval between surgery and diagnosis of new SqCC/CIS.
CIS, carcinoma in situ; LLL, left lower lobe; LMB, left main bronchus; LUL, left upper lobe; RIB, right intermediate bronchus; RLL, right lower lobe; RML, right middle lobe; RUL, right upper lobe; SqCC, squamous cell carcinoma; SD, severe dysplasia; UCLH, University College London Hospital.