Treatment and outcome of patients with acute chest syndrome and a new pulmonary opacity on CT
| At least one complete lung segment consolidation on CT | |||
|---|---|---|---|
| Parameter | No (n=55) | Yes (n=84) | p Value |
| Treatment | |||
| Maximal nasal oxygen, L/min | 4 [3–6] | 6 [4–10] | <0.01 |
| Mechanical ventilation | |||
| Non-invasive | 2 (4%) | 5 (6%) | 0.70 |
| Invasive | 1 (2%) | 3 (4%) | >0.99 |
| Antibiotic treatment | 26 (48%) | 77 (93%) | <0.01 |
| Transfusions and phlebotomies | 0.06 | ||
| Simple transfusion | 8 (15%) | 9 (11%) | |
| Partial-exchange transfusion | 20 (36%) | 49 (58%) | |
| Simple phlebotomy | 1 (2%) | 0 (0%) | |
| Total number of transfused red blood cell units (in patients with simple transfusion or partial-exchange transfusion) | 1.0 [0.0–2.0] | 2.0 [0.0–4.0] | <0.01 |
| Total volume of exsanguinated blood, mL (in patients with partial-exchange transfusion or phlebotomy) | 0 [0–350] | 275 [0–700] | 0.01 |
| Outcome | |||
| Complicated ACS* | 28 (51%) | 58 (69%) | 0.03 |
| Hospital stay, days | 8 [6–13] | 11 [7–13] | 0.09 |
| Hospital deaths | 1 (2%) | 0 (0%) | 0.40 |
Data are presented as mean±SD, median [25th–75th percentiles] or number (percentage).
*Complications included need for mechanical ventilation, transfusion or death.
ACS, acute chest syndrome.