Changes in spirometric measurement, arterial blood gas measurements and ventilator settings of patients initiating HMV between 2006 and 2012.
| Analysed parameters | 2006 | 2012 | p value | |||
| mean | SD | mean | SD | |||
| FEV1 (L/s) NMD/CWD COPD ORRF FVC (L) NMD/CWD COPD ORRF PaO2 (kPa) NMD/CWD COPD ORRF PaCO2 (kPa) NMD/CWD COPD ORRF HCO3 (mmol/L) NMD/CWD COPD ORRF | 0.9 0.7 1.6 1.1 1.2 2.0 9.9 8.0 9.1 7.7 7.5 6.9 30 33 31 | 0.5 0.3 0.7 0.5 0.5 0.8 1.4 1.2 1.6 0.6 1.1 1.1 3 4 4 | 1.1 0.6 1.9 1.4 1.4 2.4 9.8 8.5 8.9 7.5 8.6 6.6 33 37 29 | 0.4 0.2 1.2 0.4 0.5 1.4 2.5 1.9 1.5 1.6 1.2 1.4 5 5 4 | 0.2 0.8 0.1 0.04* 0.4 0.1 0.9 0.3 0.6 0.01* <0.01* 0.2 0.04* <0.01* 0.03* | |
| IPAP (cmH2O) | Median | IQR | Median | IQR | ||
| NMD/CWD | 16 | 14-18 | 20 | 17-24 | <0.01 | |
| COPD | 24 | 20-25 | 26 | 24-28 | <0.01 | |
| ORRF | 22 | 18-25 | 24 | 19-28 | <0.05 | |
| EPAP (cmH2O) | ||||||
| NMD/CWD | 5 | 4-8 | 4 | 3-5 | <0.01 | |
| COPD | 6 | 5-10 | 4 | 3-5 | <0.01 | |
| ORRF | 12 | 10-16 | 12 | 10-19 | 0.1 | |
↵* Significant difference (p value <0.05) between 2006 and 2012