Known-groups validity: E-RS Mean (SD) scores by chronic bronchitis diagnosis, smoking status, and rescue medication use
| Chronic bronchitis | Smoking status | Rescue medication use† | |||||||
|---|---|---|---|---|---|---|---|---|---|
| E-RS scores* | Yes (n=51) | No (n=137) | p Value‡ | Current smoker (n=58) | Ex-smoker (n=130) | p Value‡ | 3 or more puffs (n=58) | No (n=94) | p Value‡ |
| RS-Total | 15.0 (6.2) | 10.8 (6.6) | 0.0001 | 14.8 (6.8) | 10.6 (6.3) | <0.0001 | 14.7 (6.1) | 9.9 (6.3) | <0.0001 |
| RS-Breathlessness | 7.3 (3.4) | 5.4 (3.7) | 0.0018 | 6.9 (3.7) | 5.5 (3.6) | 0.0183 | 7.6 (3.4) | 4.7 (3.4) | <0.0001 |
| RS-Cough & Sputum | 4.5 (2.1) | 3.1 (2.2) | 0.0002 | 4.7 (2.0) | 3.0 (2.2) | <0.0001 | 4.3 (2.0) | 3.0 (2.3) | 0.0009 |
| RS-Chest Symptoms | 3.2 (2.3) | 2.2 (2.0) | 0.0059 | 3.2 (2.4) | 2.1 (1.9) | 0.0012 | 2.9 (2.1) | 2.2 (2.1) | 0.0453 |
*RS-Total and RS-domain score ranges are as follows with the higher values indicating greater severity of respiratory symptoms: RS-Total scores range from 0 to 40; RS-Breathlessness scores range from 0 to 17; RS-Cough & Sputum scores range from 0 to 11; and RS-Chest Symptoms scores range from 0 to 12.
†Study Day 1.
‡Student t test.
E-RS, Exacerbations of Chronic Pulmonary Disease Tool-Respiratory Symptoms.