Abstract S113 Table 1.

Dexamethasone inhibition of NTHI induced mediator production in alveolar macrophages.

Cytokine Percentage inhibition by 1µM dexamethasone
COPDSmokers
TNF-α 42.5% ***#67.3% ***#
IL-6 26% **#43.2% **#
IL-8 -29% 16.2%
IL-10 44% ***38.7% **

  • ↵**,*** = significant bellow dimethyl sulfoxide (DMSO) control (p< 0.01, 0.001)

  • ↵# = significant difference between COPD and Smokers (p<0.05)