Table 3

Factors associated with death within 90 days of surgery for patients with records of performance status, stage and lung function

	Overall N=3319		Died within 90 days of surgery (n=169)
	n	%	n	%	OR	95% CI	Adjusted OR*	95% CI
Sex
Women	1482	44.7	57	3.8	1.00		1.00
Men	1837	55.3	112	6.1	1.62	1.17 to 2.25	1.24	0.88 to 1.75
						p=0.0030		p=0.2196
Age group
<55	268	8.1	5	1.9	0.27	0.11 to 0.68	0.32	0.12 to 0.83
55–59	272	8.2	8	2.9	0.43	0.20 to 0.92	0.40	0.18 to 0.88
60–64	583	17.6	18	3.1	0.45	0.26 to 0.78	0.45	0.25 to 0.80
65–69	665	20.0	29	4.4	0.64	0.40 to 1.04	0.61	0.37 to 1.00
70–74	694	20.9	46	6.6	1.00		1.00
75–79	566	17.1	40	7.1	1.07	0.69 to 1.66	1.15	0.73 to 1.82
80–84	236	7.1	18	7.6	1.16	0.66 to 2.05	1.43	0.80 to 2.58
85+	35	1.1	5	14.3	2.35	0.87 to 6.34	3.17	1.12 to 9.01
						p<0.0001**		p<0.0001**
Ethnicity
White	2769	83.4	146	5.3	1.00
Black	21	0.6	–	–
Asian	28	0.8	–	–
Other	24	0.7	–	–
Missing	477	14.4	23	4.8	0.91	0.58 to 1.43
Townsend quintile
1	448	13.5	14	3.1	1.00
2	512	15.4	23	4.5	1.46	0.74 to 2.87
3	531	16.0	39	7.3	2.46	1.32 to 4.59
4	615	18.5	28	4.6	1.48	0.77 to 2.84
(most deprived) 5	772	23.3	38	4.9	1.60	0.86 to 3.00
Missing	441	13.3	27	6.1	2.02	1.05 to 3.91
						p=0.3325**
Performance status
0	1674	50.4	51	3.0	1.00		1.00
1	1390	41.9	97	7.0	2.39	1.69 to 3.38	1.89	1.31 to 2.72
2	215	6.5	19	8.8	3.08	1.78 to 5.33	2.39	1.34 to 4.28
3–4	40	1.2	2	5.0	1.67	0.39 to 7.13	1.67	0.27 to 5.11
						p<0.0001**		p=0.0055**
Predicted FEV₁
>80%	1508	45.4	58	3.8	1.00		1.00
60–79%	1145	34.5	58	5.1	1.33	0.92 to 1.94	1.25	0.85 to 1.84
40–59%	557	16.8	43	7.7	2.09	1.39 to 3.14	2.01	1.30 to 3.10
<40%	109	3.3	10	9.2	2.53	1.25 to 5.09	2.78	1.31 to 5.88
						p=0.0001**		p=0.0004**
Charlson index
0–1	2508	75.6	115	4.6	1.00		1.00
≥2	811	24.4	54	6.7	1.22	1.03 to 1.44	1.19	1.00 to 1.42
						p=0.0233**		p=0.0514
Stage
IA	949	28.6	30	3.2	1.00		1.00
IB	1237	37.3	63	5.1	1.64	1.06 to 2.56	1.42	0.90 to 2.25
IIA	131	3.9	4	3.1	0.96	0.33 to 2.78	0.77	0.26 to 2.27
IIB	614	18.5	41	6.7	2.19	1.35 to 3.55	1.70	1.01 to 2.87
IIIA	388	11.7	31	8.0	2.66	1.59 to 4.46	2.18	1.25 to 3.81
						p=0.0001**		p=0.0085**
Side
Right	1841	55.5	96	5.2	1.00
Left	1365	41.1	64	4.7	0.89	0.65 to 1.24
Other	18	0.5	1	5.6	1.07	0.14 to 8.12
Missing	95	2.9	8	8.4	1.67	0.79 to 3.55
						p=0.4988
Histology (preoperative)
Adenocarcinoma	1155	34.8	43	3.7	1.00		1.00
Squamous cell	1151	34.7	74	6.4	1.78	1.21 to 2.61	1.08	0.72 to 1.63
NSCLC NOS	662	19.9	35	5.3	1.44	0.91 to 2.28	1.03	0.64 to 1.66
Other	82	2.5	3	3.7	0.98	0.30 to 3.24	0.83	0.25 to 2.82
Missing	269	8.1	14	5.2	1.42	0.77 to 2.63	1.37	0.73 to 2.60
						p=0.0538		p=0.8873
Procedure
Segmentectomy/wedge	441	13.3	16	3.6	0.88	0.51 to 1.52	0.76	0.44 to 1.33
Lobectomy	2275	68.5	93	4.1	1.00		1.00
Bi-lobectomy	131	3.9	12	9.2	2.37	1.26 to 4.44	2.37	1.23 to 4.60
Pneumonectomy	335	10.1	40	11.9	3.18	2.15 to 4.70	3.36	2.17 to 5.20
Other	137	4.1	8	5.8	1.46	0.69 to 3.06	1.10	0.51 to 2.36
						p<0.0001		p<0.0001

*ORs are adjusted for all other factors for which adjusted ORs are given. All p values calculated using likelihood ratio test.
**Likelihood ratio test p for trend.
FEV₁, forced expiratory volume in 1 s; NSCLC, non-small cell lung cancer; NOS, not otherwise specified; PS, performance status.