Table 1

Patient demographics and baseline characteristics

Number of subjects5156
Median age (years)12 (range 6–41)11 (range 6–47)
Age 6–11 years2531
Age 12–17 years1814
Age 18–47 years811
Pseudomonas positive/negative17/3419/37
FVC percent predicted100.7±13.894.3±14.8
FEV1 percent predicted92.9±17.285.8±18.0
FEF25–75 percent predicted79.7±31.673.8±32.5
Body mass index18.43±3.3718.62±4.55
Delta F508 homozygous47%43%
Regular use of inhaled bronchodilator88%88%
Regular use of hypertonic saline12%13%
Regular use of rhDNase25%30%
Regular use of inhaled steroids55%48%
Regular use of an inhaled antibiotic24%20%
Regular use of azithromycin19%14%
Number of patients performing ACT once daily1212
  • Data for body mass index, FVC, FEV1 and FEF25–75 are represented as mean±SD.

  • ACT, airway clearance technique; FEF25–75, forced expiratory flow between 25% and 75% of vital capacity; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; HFCWO, high frequency chest wall oscillation; PEP, positive expiratory pressure.