Table 1

Summarised characteristics of patients with non-cystic fibrosis bronchiectasis

Gender (male:female)13:28
RangeMean (± SD)
Age (years)37–7462.9 (± 6.9)
FEV1% pre bronchodilator35–10272.9 (± 15.3)
FEV1% post bronchodilator41–10476.8 (± 14.4)
Duration of bronchiectasis (years)4–7040.7 (± 22.9)
Pulmonary exacerbations reported in the preceding 12 months (n)2–125.0 (±2.8)
LCS5.5–2014.2 (± 4.0)
SGRQ total19–8039.4 (± 16.4)
SGRQ symptoms24–10059.8 (± 20.9)
C-reactive protein (mg/litre)0–184.7 (± 4.8)
Sputum neutrophils (×105/ml)56–611382.8 (± 122.3)
Sputum % neutrophils39–9983.7 (± 15.3)
Pseudomonas aeruginosa positive (standard culture)*27% (11 of 41)
Haemophilus influenzae positive (standard culture)*29% (12 of 41)
ICS use
 Alone12% (5 of 41)
 In combination with LABA44% (18 of 41)
  • Of the 41 subjects, 40 were Caucasian and one was Maori.

  • *Standard diagnostic microbiology performed on separate sample to that used for molecular analysis.

  • FEV1%, forced expiratory volume in 1 s as a percentage of the predicted value; ICS, inhaled corticosteroid; LABA, long-acting β agonist; LCS, Leicester Cough Score, lower scores indicate worse cough symptoms, range 3–21; SGRQ, St George's Respiratory Questionnaire—range 1–100, lower scores indicate better quality of life, symptoms component measures the effect of respiratory symptoms; sputum % neutrophils, neutrophils in induced sputum as a percent of total non-squamous cells.