Lung function impairment in IPF and SSc-ILD according to carriage of the T allele
| Non-carrier | Carrier | p Value | |
|---|---|---|---|
| IPF | n=41 | n=66 | |
| CPI | 54.0 (0.27–65.9) | 50.0 (18–73.2) | 0.43 |
| FVC, % predicted | 65.9 (41–132) | 72.0 (28.6–143) | 0.78 |
| Tlco, % predicted | 38.9 (23.4–101) | 40.0 (18.1–76.8) | 0.92 |
| SSc-ILD | n=156 | n=50 | |
| CPI | 39.1 (−0.65–68.1) | 41.2 (3.9–68.3) | 0.39 |
| FVC, % predicted | 80.3 (40–145) | 82.3 (52.6–119) | 0.99 |
| Tlco, % predicted | 55.4 (20–107.7) | 54.6 (22.3–91.3) | 0.30 |
Data are presented as median at presentation (range).
CPI, composite physiological index; FVC, forced vital capacity; IPF, idiopathic pulmonary fibrosis; SSc-ILD, systemic sclerosis associated interstitial lung disease; Tlco, lung carbon monoxide transfer factor.