Pulmonary function in sarcoidosis according to carriage of the minor T allele
| Non-carrier | Carrier | p Value | |
|---|---|---|---|
| At presentation | n=140 | n=38 | |
| Tlco | 75.3 (25.3–125.4) | 74.6 (35–109.7) | 0.60 |
| FEV1 | 92.8 (14.1–136) | 87.5 (22.8–128.5) | 0.26 |
| FVC | 97.9 (42.4–143.8) | 94.6 (43.2–146.5) | 0.74 |
| At 2 years | n=121 | n=28 | |
| Tlco | 76.6 (24.1–126.5) | 72.0 (38.4–110.4) | 0.37 |
| FEV1 | 89.1 (13.9–134.5) | 93.5 (21.6–128.3) | 0.53 |
| FVC | 98.5 (47.8–135.9) | 100.9 (54.4–143.2) | 0.92 |
| At 4 years | n=114 | n=26 | |
| Tlco | 76.1 (11.7–126.7) | 75.6 (46–119) | 0.95 |
| FEV1 | 89.7 (32.8–142.2) | 90.2 (34.2–135.9) | 0.64 |
| FVC | 98.1 (35.1–143) | 100.3 (64.4–150.5) | 0.47 |
Data are presented as median (range) percentage predicted.
FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; Tlco, lung carbon monoxide transfer factor.