Patients with COPD | |||
---|---|---|---|
Controls | Exacerbated | Stable | |
Subjects | 20 | 16 | 11 |
Age (years) | 55±10 | 66±10 | 64±8 |
Current smokers % | 52.6 | 46.1 | 57.1 |
Smoking history | 23.4±19.4 | 51±18.7* | 50.5±14.8* |
Pack-years† | |||
FEV1% predicted | 98.6±10.4 | — | 51.2±17.1* |
FEV1/FVC % | 79.8±8.2 | — | 48.8±10.8* |
Neutrophils/mm3 | 5529±1777 | 6729±2326 | 5136±1630 |
Data are presented as mean±SD or %, unless otherwise stated.
*p<0.05 vs controls.
†1 pack-year represents 20 cigarettes per day for 1 year.
COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity.