Associations between adult onset asthma and ever working in a mutually exclusive ASJEM exposure risk group by age 42
| Adult onset asthma | Adult onset asthma with airflow limitation‡ | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Exposure group | Case/total† | OR | OR* | 95% CI | p Value | Case/total† | OR* | 95% CI | p Value |
| Non-exposed | 147/1864 | 1.00 | 1.00 | – | – | 24/1567 | 1.00 | – | – |
| Ever a low-risk exposure (but never a high-risk) | 163/2087 | 0.99 | 1.20 | 0.94 to 1.52 | 0.147 | 29/1701 | 1.21 | 0.69 to 2.13 | 0.497 |
| Ever a high-risk exposure (but never a low-risk exposure) | 66/595 | 1.46 | 1.53 | 1.12 to 2.09 | 0.007 | 10/484 | 1.31 | 0.62 to 2.80 | 0.472 |
| Worked in both low-risk jobs and in high-risk jobs | 235/2542 | 1.19 | 1.34 | 1.07 to 1.68 | 0.010 | 48/2131 | 1.48 | 0.89 to 2.47 | 0.131 |
Bold type indicates conventional levels of statistical significance (p<0.05).
*Adjusted for sex, smoking, father's social class at birth, region and hay fever.
†309 individuals who had provided insufficient information to be certain regarding exposure status for their entire working life were excluded (257 without lung function measures)
‡Those with asthma but no airflow limitation were coded ‘no’ for this analysis.