Table 3

Baseline characteristics for patients used in the separate validation of the algorithm, n=50

% Predicted
Sex, M/F25/25
Age, years64 (8)
Lung function
 FEV1, litres1.1 (0.4)40.2 (15.1)
 FEV1/FVC0.41 (0.09)
DL,CO, mmol/min/kPa3.0 (1.5)36 (17)
DL,CO/VA, mmol/min/kPa/litre0.6 (0.3)44 (21)
 TLC, litres7.6 (1.6)127 (21)
 RV, litres4.4 (1.3)198 (50)
Blood gases and pulse oximetry at sea level
 PaO2, kPa9.0 (1.1)
 PaCO2, kPa5.1 (0.6)
 SpO2, %93 (3)
Six min walk test
 Distance, m425 (109)
 Exercise SpO2, %82 (4)
 Dyspnoea, Borg CR106.4 (2.2)
HAST blood gases and pulse oximetry
 PaO2, kPa6.5 (0.5)
 PaCO2, kPa4.9 (0.6)
 SaO2, %85 (4)
 SpO2, %85 (4)
  • Data are presented as n (%) and mean (SD).

  • DL,CO, diffusing capacity of the lung for carbon monoxide; FEV1%predicted, forced expiratory volume in 1 s in per cent of predicted; FVC, forced vital capacity; HAST, hypoxia-altitude simulation test; PaCO2, arterial carbon dioxide pressure; PaO2, arterial oxygen pressure; RV, residual volume; SaO2, arterial oxygen saturation; SpO2, arterial oxygen saturation by pulse oximetry; TLC, total lung capacity; VA, alveolar volume.