Univariable and multivariable logistic regression analyses for independent variables of COPD patients significantly associated with frequent exacerbation
| Variables | Univariate | Multivariate | ||
| Risk value (95% CI) | p Value | Risk value (95% CI) | p Value | |
| Age | 1.005 (0.944 to 1.071) | 0.871 | ||
| BMI | 0.866 (0.725 to 1.034) | 0.112 | ||
| PaO2 | 0.958 (0.895 to 1.026) | 0.223 | ||
| Pack-years smoking index | 1.012 (0.991 to 1.033) | 0.254 | ||
| CRP | 1.287 (0.346 to 4.781) | 0.706 | ||
| Leucocyte counts | 1.000 (1.000 to 1.001) | 0.016 | 1.000 (1.000 to 1.001) | 0.128 |
| GOLD stages | ||||
| Stage II | 7.200 (0.799 to 64.902) | 0.078 | 0.630 (0.035 to 11.239) | 0.753 |
| Stage III | 8.571 (0.907 to 81.009) | 0.060 | 0.455 (0.016 to 12.611) | 0.641 |
| Stage IV | 55.999 (5.005 to 626.577) | 0.001 | 3.380 (0.094 to 120.888) | 0.504 |
| VE-cadherin EMPs | 1.006 (1.003 to 1.009) | <0.001 | 1.001 (0.995 to 1.006) | 0.835 |
| MCAM EMPs | 1.001 (0.993 to 1.009) | 0.737 | ||
| PECAM EMPs | 1.000 (1.000 to 1.001) | 0.009 | 1.000 (1.000 to 1.001) | 0.554 |
| E-selectin EMPs | 1.022 (1.013 to 1.032) | <0.001 | 1.018 (1.006 to 1.031) | 0.003 |
Bold denotes values: p < 0.05.