Table 5

Sensitivities, specificities and predictive values of the two models at chosen cutoffs applied to the exploratory and validation cohorts and p values for a two-sample z-test comparing the sensitivities and specificities of the chosen cutoffs in the two populations

ModelsSensitivitySpecificityPositive predictive valueNegative predictive value
Model 1 (cutoff 0.15)
 Exploratory cohort76 (46 to 95)84 (72 to 92)53 (25 to 75)94 (84 to 99)
 Validation cohort60 (41 to 77)85 (77 to 91)55 (36 to 72)88 (80 to 93)
 p Values for z-test0.5070.866
Model 2 (cutoff 0.3)
 Exploratory cohort82 (48 to 98)96 (87 to 99)82 (48 to 98)96 (87 to 99)
 Validation cohort60 (36 to 81)93 (85 to 97)63 (38 to 84)92 (84 to 96)
 p Values for z-test0.3840.342
  • Note: 95% CI.