HRQL pre–post treatment in AVAPS and PS groups
| AVAPS | Fixed-level PS | |||||
| Baseline | Follow-up | p Value | Baseline | Follow-up | p Value | |
| SRI-SS (/100) | 55±16 | 66±19 | <0.001 | 51±14 | 57±15 | 0.018 |
| SRI-RC (/100) | 55±20 | 70±20 | 0.001 | 49±24 | 59±22 | 0.025 |
| SRI-PF (/100) | 50±24 | 58±26 | 0.069 | 42±20 | 47±22 | 0.139 |
| SRI-AS (/100) | 48±17 | 62±20 | 0.003 | 48±19 | 54±16 | 0.100 |
| SRI-SR (/100) | 66±20 | 72±24 | 0.116 | 67±20 | 73±18 | 0.165 |
| SRI-AX (/100) | 48±24 | 65±29 | 0.001 | 41±23 | 50±21 | 0.094 |
| SRI-WB (/100) | 55±19 | 64±21 | 0.007 | 51±16 | 55±17 | 0.303 |
| SRI-SF (/100) | 61±24 | 73±20 | 0.005 | 55±22 | 63±22 | 0.143 |
| VAS-sleep comfort (/100) | 44±30 | 57±27 | 0.026 | 33±27 | 53±22 | 0.001 |
| VAS-activity (/100) | 43±24 | 52±26 | 0.177 | 47±23 | 47±22 | 0.967 |
| VAS-fatigue (/100) | 39±23 | 59±27 | 0.001 | 42±26 | 55±28 | 0.058 |
| ESS (/24) | 11±5 | 6±5 | 0.001 | 13±6 | 7±5 | <0.001 |
| FSS (/56) | 43±14 | 34±15 | 0.014 | 45±16 | 37±18 | 0.038 |
The p values refer to paired t test analysis from initiation to follow-up values within each group.
AVAPS, average-volume-assured pressure support; ESS, Epworth Sleepiness Score; FSS, fatigue severity score (total=56; higher score indicates greater level of fatigue); HRQL, health-related quality of life; PS, pressure support; SRI-AS, Severe Respiratory Insufficiency questionnaire attendant symptoms and sleep; SRI-AX, Severe Respiratory Insufficiency questionnaire anxiety; SRI-PF, Severe Respiratory Insufficiency questionnaire physical functioning; SRI-RC, Severe Respiratory Insufficiency questionnaire respiratory complaints; SRI-SR, Severe Respiratory Insufficiency questionnaire social relationships; SRI-SS, Severe Respiratory Insufficiency questionnaire summary scale (total=100; higher score indicates higher quality of life); SRI-WB, Severe Respiratory Insufficiency questionnaire psychological wellbeing; SRI-SF, Severe Respiratory Insufficiency questionnaire social functioning; VAS, visual analogue scale (higher score indicates greater quality of life).