Correlate 1 | Correlate 2 | Pearson correlation coefficient (r) | Significance (p) | n |
Significant patient-specific pairwise correlations | ||||
Clinical: clinical correlations | ||||
FEV1 | Temperature | 0.539 | 0.047 | 14 |
FEV6 | No. CFPEs | −0.573 | 0.032 | 14 |
No. CFPEs | Age | −0.533 | 0.05 | 14 |
Genotype | Age | 0.652 | 0.012 | 14 |
PRO sum | Gender | 0.758 | 0.002* | 14 |
BMI | Nebulised colomycin | 0.621 | 0.018 | 14 |
Clinical: microbiological correlations | ||||
FEV6 | Rank abundance slope | −0.602 | 0.023 | 14 |
FEV6 | Species number | 0.549 | 0.042 | 14 |
Microbiological: microbiological correlations | ||||
Pseudomonas aeruginosa T-RF % | Rank abundance slope | −0.763 | 0.002* | 14 |
P aeruginosa T-RF % | Species number | −0.763 | 0.002* | 14 |
P aeruginosa T-RF % | Bray-curtis similarity | −0.715 | 0.004 | 14 |
Species number | Rank abundance slope | −0.711 | 0.004 | 14 |
Significant patient independent pairwise correlations across all samples | ||||
FEV1 | Species number | 0.771 | 0.0001 | 168 |
FEV6 | Species number | 0.748 | 0.0001 | 168 |
FEV1 | Rank abundance slope | −0.672 | 0.0001 | 168 |
FEV6 | Rank abundance slope | −0.712 | 0.0001 | 168 |
FEV1 | P aeruginosa T-RF % | −0.706 | 0.0001 | 168 |
FEV6 | P aeruginosa T-RF % | −0.691 | 0.0001 | 168 |
↵* Correlations for which p<0.05 after Bonferroni correction.
BMI, body mass index; CFPE, cystic fibrosis pulmonary exacerbation; FEV1, forced expiratory volume in 1 s; FEV6, forced expiratory volume in 6 s; PRO, patient-reported outcome; T-RF, terminal restriction fragment.