Epithelial eotaxins in relation to exacerbations
No ER visit | ER visit | p Value | <3 oral CS bursts | >3 oral CS bursts | p Value | |
---|---|---|---|---|---|---|
Eotaxin-2 protein (pg/million cells) | 5 (5–28) | 30 (5–94) | 0.04 | 5 (5–27) | 42 (5–137) | 0.004 |
Eotaxin-2 mRNA/GAPDH | 0.16 (0.07–0.27) | 0.26 (0.12–0.26) | 0.06 | 0.15 (0.08–0.29) | 0.32 (0.18–0.85) | 0.006 |
Eotaxin-3 mRNA/GAPDH | 0.10 (0.03–0.38) | 0.34 (0.13–0.88) | 0.01 | 0.09 (0.15–0.66) | 0.3 (0.12–0.71) | 0.051 |
All values median (25th–75th percentiles).
CS, corticosteroid; ER, emergency room; GAPDH, glyceraldehyde 3-phosphate dehydrogenase.