Table 6

Consistency of reversibility status and clinical outcomes

OutcomeConsistently* reversibleConsistently* irreversiblep Value adjusted for FEV1 % predictedp Value adjusted for GOLD stage
Subject death8 (4%)83 (6%)0.6080.462
Exacerbation rate0.8 (1.1)1.3 (1.6)0.0320.009
Hospitalised due to COPD exacerbation15 (7%)206 (15%)0.1590.089
Subject withdrawal29 (13%)186 (14%)0.2970.455
  • * Consistent = reversible or irreversible according to American Thoracic Society/European Respiratory Society criteria on three of four occasions.

  • COPD, chronic obstructive pulmonary disease; FEV1, forced expiratory volume in 1 s; GOLD, Global initiative for chronic Obstructive Lung Disease.