Summary of peak expiratory flow (PEF)-derived variables, asthma control, exacerbations and quality of life indices during the observed period in the two studies
| Study 1 (mild to moderate) | Study 2 (severe) | p Value | |
| Correlation exponent α | 0.78±0.18 | 0.78±0.14 | 0.995 |
| Mean PEF, l/min | 428±101 | 296±124 | <0.001 |
| Mean PEF, percentage of predicted | 78.9±15.9 | 56.0±19.1 | <0.001 |
| Number of subjects (%) with GINA score of | |||
| Controlled (≤1) | 47 (36) | 3 (2) | <0.001* |
| Partially controlled (between 1 and 2) | 75 (57) | 50 (31) | |
| Uncontrolled (= 2) | 10 (8) | 106 (67) | |
| GINA score, % of weeks spent uncontrolled | 29.3±33.0 | 86.0±27.6 | <0.001† |
| Asthma Control Questionnaire score, mean over period | – | 2.36 (0.81–3.74) | – |
| Lowest tertile | – | 1.48 (0.64–2.05) | |
| Medium tertile | – | 2.36 (2.12–2.64) | |
| Highest tertile | – | 3.12 (2.74–4.02) | |
| Number of exacerbations over period | 1 (0–10) | 2 (0–11) | 0.017 |
| Number of subjects having | |||
| No exacerbations (%) | 58 (44) | 43 (27) | 0.003 |
| ≥1 exacerbation(s) (%) | 74 (56) | 116 (73) | |
| Asthma Quality of Life Questionnaire score, mean over period | – | 4.67 (2.98–6.44) | – |
| Lowest tertile | – | 3.69 (2.38–4.19) | |
| Medium tertile | – | 4.68 (4.25–5.11) | |
| Highest tertile | – | 5.81 (5.19–6.58) | |