Characteristics of 288 lung transplantations
| Close to a major road (≤171 m, n=96)* | Farther away from a major road (>171 m, n=192)* | p-Value | |
| Number of BOS events, n (%) | 49 (51%) | 69 (35%) | 0.01 |
| Number of deaths, n (%) | 27 (28%) | 34 (18%) | 0.04 |
| Age at transplantation (years) | 47.5±14.3 | 46.3±13.9 | 0.49 |
| Mean date of transplantation (SD of year) | 14/08/2004±3.2 | 20/03/2004±3.0 | 0.30 |
| Donor age (years)† | 40.0±14.5 | 38.4±13.1 | 0.32 |
| Women, n (%) | 51 (53%) | 78 (41%) | 0.04 |
| Underlying disease, n (%) | 0.04 | ||
| Emphysema (COPD) | 47 (49%) | 77 (40%) | |
| Pulmonary fibrosis | 14 (15%) | 35 (18%) | |
| Cystic fibrosis | 6 (6%) | 38 (20%) | |
| α1-Antitrypsin deficiency | 6 (6%) | 10 (5%) | |
| Pulmonary arterial hypertension | 8 (8%) | 9 (5%) | |
| Others | 15 (16%) | 23 (12%) | |
| Double lung transplantation, n (%) | 74 (77%) | 143 (74%) | 0.63 |
| Ischaemic time (min) | 338±109 | 357±100 | 0.16 |
| Acute rejections during follow-up | 0.75 | ||
| None | 55 (57%) | 101 (52%) | |
| Once | 27 (28%) | 59 (31%) | |
| Twice or more | 14 (15%) | 32 (17%) | |
| CMV infection ≥1, n (%) | 17 (18%) | 24 (13%) | 0.23 |
| Other infections | 0.81 | ||
| None | 49 (51%) | 97 (51%) | |
| Once | 24 (25%) | 54 (28%) | |
| Twice of more | 23 (24%) | 41 (21%) | |
| Pseudomonas colonisation | 32 (33%) | 67 (35%) | 0.77 |
| Gastro-oesophageal reflux† | 42 (33%) | 86 (67%) | 0.93 |
| Smokers before transplantation,‡ n (%) | 35 (64%) | 66 (56%) | 0.37 |
| Smokers after transplantation,‡ n (%) | 8 (14%) | 12 (9%) | 0.33 |
| Socioeconomic status | 0.72 | ||
| Low | 55 (57%) | 106 (55%) | |
| Middle | 33 (34%) | 64 (33%) | |
| High | 8 (8%) | 22 (11%) | |
| Interpolated PM10, μg/m3 | 31.2±4.8 | 29.6±5.1 | 0.01 |
| Interpolated NO2, μg/m3 | 26.8±7.6 | 25.7±7.7 | 0.24 |
Data are means±SD or numbers (%). PM10, particulate matter with a diameter less than 10 μm.
BOS, bronchiolitis obliterans syndrome; COPD, chronic obstructive pulmonary disease.
* Patients were assigned to categories according to distance from home to major roads based on the cut-off value between the lowest tertile and the next tertile of the distribution of distances.
† Information missing for donor age in one person, and for gastro-oesophageal reflux in 49 people.
‡ Reliable information available in 190 patients.