Top 10 downregulated microRNAs in lungs from subjects with COPD compared with smokers without COPD
| miRNA | Fold difference (COPD/normal smokers) | p Value | pFDR value |
| hsa-miR-923 | −5.06 | 5.88E-06 | 2.91E-05 |
| hsa-miR-937 | −2.36 | 1.89E-06 | 1.08E-05 |
| hsa-miR-422a | −2.12 | 1.45E-06 | 8.74E-06 |
| hsa-miR-576-3p | −2.06 | 1.57E-06 | 9.22E-06 |
| hsa-miR-513a-5p | −2.06 | 3.57E-04 | 8.54E-04 |
| hsa-miR-25* | −2.01 | 2.10E-07 | 1.56E-06 |
| hsa-miR-99b* | −1.81 | 1.23E-05 | 5.25E-05 |
| hsa-miR-125b-1* | −1.75 | 1.38E-05 | 5.70E-05 |
| hsa-miR-24 | −1.75 | 1.59E-04 | 4.49E-04 |
| hsa-miR-187* | −1.64 | 3.14E-04 | 8.04E-04 |
↵* indicates miRNA on the opposite arm of the hairpin during processing.
COPD, chronic obstructive pulmonary disease; pFDR, positive false discovery rate.