Table 1

Relevant data and genetic findings in 18 adult patients with allergic bronchopulmonary aspergillosis (ABPA)

Subject no.Age (years)*GenderSweat (Cl) (mmol/l)BCCFTR mutations
Princeps study2 Current study
130M17+F508delF508del/D1152H
630M32+L997F/L997F
774M34G576A/D443Y–R668C
855M36+R1070W/3659delC
265M33+F508delF508del
364M6+G542XG542X
458F8+R117HR117H
563FNA+1717-1G→A1717-1G→A
959F14+R75Q
1047F19+L967S
1168F21+I177F
1267F34V1153E
1346FNA+
1460F37+
1584M23+
1679F40+
1763M15+
1858M13
  • * In 1997.

  • Investigated set of mutations: F508 del, G542X N1303K, R117H, 621+1G→T, R334W, ΔI507, W1282X, R553X, R1162X, 1717–1G→A, G551D, 3849+10kbC→T; BC: bronchiectasis (high-resolution CT scan).

  • CFTR, cystic fibrosis transmembrane conductance regulator; F, female; M, male; NA, declined sweat testing.