Table 3

Time course of changes in the transcutaneous partial pressure of carbon dioxide (Ptco2) in the treatment groups

(1) The mean change in Ptco2 (mm Hg)
TimeHigh concentration O2mean (SD)Titrated O2mean (SD)Difference (95% CI)p Value
20 min2.8 (4.1)0.3 (3.6)2.5 (1.0 to 4.0)0.001
40 min3.0 (4.7)0.4 (3.8)2.6 (0.9 to 4.3)0.002
60 min3.4 (4.5)0.8 (4.1)2.6 (0.9 to 4.3)0.003
(2) The proportion of patients with a rise in Ptco2 ≥4 mm Hg
TimeHigh concentration O2N (%)Titrated O2N (%)RR (95% CI)p Value
20 min15 (30%)7 (13%)2.3 (1.0 to 5.1)0.038
40 min21 (42%)8 (15%)2.8 (1.4 to 5.7)0.002
60 min22 (44%)10 (19%)2.3 (1.2 to 4.4)0.006