Table 1

Characteristics of participants taking part in the DNA damage/repair and DNA fragility studies

ParticipantsNAgeSexSmoking historyPack-yearsChronic bronchitisFEV1 % predFEV1/FVC%
Non-smokers751.6 (17.5)3M/4FAll never00NDND
Smokers1569.5 (5.5)13M/2F
  • 6 ex,

  • 5 current

48.9 (28.6)994.6 (19.9)75.4 (4)
COPD1169 (6.7)11M
  • 5 ex,

  • 4 current

43.6 (26.6)477.7 (15.6)64 (1.4)
  • For patients with chronic obstructive pulmonary disease (COPD) and smokers with normal lung function predicted forced expiratory volume in 1 s (FEV1% pred) and FEV1/forced vital capacity (FVC)% are post-bronchodilator values.

  • ND, not done in five participants; two had a FEV1/FVC ratio of 77(5.6)% of predicted.

  • M, male; F, female. Data expressed as mean (SD).