Table 4

Decline in FEV1 and FVC over a 20-year follow-up in British men aged 40–59 years in 1978–1980 according to combined childhood and adult social class

Childhood and adult social classAdjusted for age and baseline valuesFurther adjusted for cigarette smokingFurther adjusted for baseline BMI, physical activity, bronchitis, asthma
Mean change in FEV1 in litres (SE) (N=3619)
 Childhood and adult—non-manual (n=772)−0.74 (0.02)−0.76 (0.02)−0.76 (0.02)
 Childhood non-manual and adult manual social class (n=284)−0.86 (0.03)−0.85 (0.03)−0.85 (0.03)
 Childhood manual and adult non-manual social class (n=1011)−0.82 (0.01)−0.83 (0.01)−0.83 (0.01)
 Childhood manual and adult manual social class (n=1552)−0.94 (0.01)−0.92 (0.01)−0.92 (0.01)
 p Value*<0.001<0.001<0.001
Mean change in FVC in litres (SE) (N=3620)
 Childhood and adult—non-manual (n=772)−1.02 (0.02)−1.05 (0.02)−1.04 (0.02)
 Childhood non-manual and adult manual social class (n=284)−1.11 (0.04)−1.10 (0.04)−1.10 (0.04)
 Childhood manual and adult non-manual social class (n=1011)−1.07 (0.02)−1.08 (0.02)−1.08 (0.02)
 Childhood manual and adult manual social class (n=1553)−1.18 (0.02)−1.16 (0.02)−1.16 (0.02)
 p Value*<0.001<0.001<0.001
  • * p Value for difference in mean decline in four groups.