Table 2

Cox proportional hazards model fitted to estimate the RR of death for males versus females and adjusted for the covariates histology, stage, age and diagnostic period

HR (95% CI)p Value
Sex
(adjusted for histology, stage, age and diagnostic period)
 Female*
 Male1.137 (1.109 to 1.166)<0.001
Histology
(adjusted for stage, age and diagnostic period)
 Adenocarcinoma*
 NOS1.198 (1.156 to 1.241)<0.001
 Squamous cell carcinoma0.976 (945 to 1.009)0.150
 Small cell carcinoma1.170 (1.132 to 1.210)<0.001
 Large cell carcinoma1.122 (1.062 to 1.185)<0.001
Stage
(adjusted for histology, age and diagnostic period)
 Localised disease*
 Regional disease1.539 (1.486 to 1.594)<0.001
 Metastatic disease3.367 (3.257 to 3.481)<0.001
Age (years)
(adjusted for histology, stage and diagnostic period)
 0–49*
 50–591.103 (1.039 to 1.171)0.001
 60–691.274 (1.204 to 1.347)<0.001
 70–791.661 (1.570 to 1.756)<0.001
 80 and over2.508 (2.354 to 2.673)<0.001
Diagnostic period
(adjusted for histology, stage and age)
 1988–1992*
 1993–19970.954 (0.922 to 0.987)0.007
 1998–20020.831 (0.804 to 0.860)<0.001
 2003–20070.714 (0.690 to 0.738)<0.001
  • * Reference group.

  • NOS, not otherwise specifed.