Univariate analysis of 1-year survival after tracheotomy in patients with ALS
| HR (95% CI) | p Value | |
| Sex | 0.725 (0.17 to 3.03) | 0.421 |
| Age (65.02 years) | 1.042 (0.94 to 1.14) | 0.389 |
| BMI (25.51 kg/m2) | 1.188 (0.94 to 1.49) | 0.137 |
| Onset | 0.279 (0.05 to 1.38) | 0.119 |
| ALSFRS-R (11.02) | 0.906 (0.75 to 1.08) | 0.287 |
| NBS (11.23) | 0.957 (0.86 to 1.06) | 0.418 |
| Time from ALS onset (41.29 months) | 0.997 (0.97 to 1.01) | 0.737 |
| FVC (0.99 l) | 0.701 (0.15 to 3.27) | 0.651 |
| %FVC (39.75%) | 0.988 (0.95 to 1.02) | 0.552 |
| MIC (1.26 l) | 1.264 (0.43 to 3.64) | 0.665 |
| PCF (2.13 l/s) | 0.923 (0.45 to 1.85) | 0.821 |
| PCFMIC (2.40 l/s) | 0.886 (0.47 to 1.65) | 0.704 |
| PCFMI-E (3.12 l/s) | 1.068 (0.55 to 2.05) | 0.845 |
| PImax (−28.53 cm H2O) | 1.011 (0.96 to 1.06) | 0.686 |
| PEmax (44.14 cm H2O) | 0.991 (0.95 to 1.02) | 0.566 |
| Hours with MV (17.89 h) | 1.164 (0.98 to 1.38) | 0.080 |
| Home NIV prior to tracheotomy | 1.000 (0.48 to 2.07) | 1.000 |
| Home MAC prior to tracheotomy | 1.000 (0.48 to 2.05) | 1.000 |
ALS, amyotrophic lateral sclerosis; ALSFRS-R, revised amyotrophic lateral sclerosis functional rating scale; BMI, body mass index; FVC, forced vital capacity; %FVC, predicted FVC; MAC, mechanically assisted cough; MIC, maximum insufflation capacity; NBS, Norris bulbar subscore; NIV, non-invasive ventilation; PCF, peak cough flow; PCFMIC, manually assisted PCF; PCFMI-E, mechanically assisted PCF; PEmax, maximum expiratory pressure; PImax, maximum inspiratory pressure.