Gene name | Gene ID | P Value | Fold change | Function |
UNKNOWN | 1568375_at | 0.0004 | 2.83 | Defence response |
TPST1 | 204140_at | <0.0001 | 2.78 | Peptidyl-tyrosine sulfation /// inflammatory response |
ANKRD33 | 242209_at | <0.0001 | 2.73 | Transcription Factor |
ZBTB16 | 228854_at | 0.009 | 2.68 | Transcription Factor |
DAAM2 | 212793_at | 0.0002 | 2.58 | Cellular component organisation and biogenesis |
TKTL1 | 214183_s_at | <0.0001 | 2.57 | Glucose catabolic process /// metabolic process |
IL18R1 | 206618_at | <0.0001 | 2.47 | Signal transduction /// innate immune response |
TANK | 237609_at | 0.0007 | 2.43 | Signal Transduction with TRAF |
KIAA1727 | 226599_at | <0.001 | 2.42 | Cellular component organisation and biogenesis |
EGR3 | 1562247_at | <0.001 | 2.41 | Transcription regulator |
ENPP3 | 232737_s_at | <0.0001 | −2.50 | Phosphate metabolic process |
CPE | 201116_s_at | 0.003 | −2.55 | Protein modification process /// proteolysis |
C5orf4 | 220751_s_at | 0.0006 | −2.59 | Metabolic process |
FABP4 | 235978_at | 0.003 | −2.60 | Cytokine production /// negative regulation of protein kinase activity |
SPRR2G | 236119_s_at | 0.002 | −2.61 | Epidermis development /// keratinocyte differentiation |
SYTL4 | 229991_s_at | <0.0001 | −2.62 | Transport /// intracellular protein transport /// exocytosis |
CADPS2 | 219572_at | 0.0004 | −2.63 | Transport /// exocytosis /// protein transport |
ADPN | 233030_at | 0.0003 | −2.85 | Metabolic process /// lipid catabolic process |
BACE1 | 222463_s_at | 0.0009 | −2.93 | Proteolysis /// proteolysis |
TPD52L1 | 203786_s_at | <0.0001 | −3.07 | G2/M transition of mitotic cell cycle /// DNA fragmentation during apoptosis |
The 10 most highly up and down regulated genes are shown. Function was obtained by mapping to GO Processes or manual literature mapping. Positive fold change values indicate increase in LAAH (more emphysema) compared to LAAL (less emphysema).