Adjusted associations between measures of pulmonary inflammation and BMI z-score
Log10 of variables | Change in BMI z-score | SE | p Value | 95% CI |
Free NE | −0.43 | 0.19 | 0.022 | −0.79 to −0.06 |
Neutrophil number | −0.23 | 0.19 | 0.224 | −0.60 to 0.14 |
IL-6 | −0.22 | 0.27 | 0.41 | −0.74 to 0.30 |
TNFα | 0.46 | 1.28 | 0.721 | −2.05 to 2.96 |
MPO | −0.20 | 0.22 | 0.356 | −0.63 to 0.23 |
IL-1β | −0.25 | 0.24 | 0.293 | −0.72 to 0.22 |
IL-8 | −0.18 | 0.16 | 0.271 | −0.50 to 0.14 |
Data shown represent independent associations for each measure of inflammation with BMI. Models were adjusted for gender, antistaphylococcal antibiotic prophylaxis, presence of respiratory symptoms and centred-age squared.
BMI, body mass index; IL, interleukin; MPO, myeloperoxidase; NE, neutrophil elastase; TNF, tumour necrosis factor.