Clinical characteristics of children with CF (n=60 unless otherwise indicated)
| N (%) | |
| Sex (% boys) | 22 (36.7%) |
| Age at diagnosis: median (range) | 9.3 (0–169) weeks |
| Genotype | |
| Homozygous ∆ F508 | 38 (63.3%) |
| Heterozygous ∆ F508/Other | 16 (26.7%) |
| Other/Other | 6 (10.0%) |
| Mode of presentation | |
| Meconium Ileus &/or antenatal bowel pathology | 25 (41.7%) |
| Failure to thrive | 16 (26.7%) |
| Chest infection | 8 (13.3%) |
| Chest infection & failure to thrive | 9 (15.0%) |
| Family history & asymptomatic | 2 (3.3%) |
| Clinical details at time of test | |
| Wheeze on auscultation (n=59) | 3 (5%) |
| Cough in the preceding 7 days (n=59) | 39 (66%) |
| Crackles/crepitations on Auscultation (n=59) | 6 (10.2%) |
| Pseudomonas status36 | |
| Never | 11 (18.3%) |
| Ever | 23 (38.3%) |
| Current | 26 (43.3%) |
| Use of antibiotics for respiratory exacerbations in the past 12 months | |
| Oral antibiotics (n=58) | 45 (77.6%) |
| IV antibiotics (n=58) | 23 (39.7%) |