The distribution of high-sensitivity troponin T by relevant covariables in 99 patients hospitalised for acute exacerbation of chronic obstructive pulmonary disease
High-sensitivity troponin T, ng/l | p Value | |||
0.0–13.9 (n=26) | 14.0–39.9 (n=37) | ≥40.0 (n=36) | ||
Female, n (%) | 17 (65) | 16 (43) | 14 (39) | 0.097 |
Age (years), mean (SD) | 65.0 (6.3) | 71.6 (8.8) | 76.3 (7.9) | <0.001 |
Medical history | ||||
FEV1/FVC, mean (SD)* | 0.44 (0.14) | 0.46 (0.13) | 0.46 (0.15) | 0.772 |
FEV1 litres, mean (% of predicted)* | 0.91 (35) | 0.96 (37) | 0.91 (39) | 0.687 |
BMI kg/m2, mean (SD)* | 24.1 (5.4) | 22.1 (5.1) | 22.3 (5.1) | 0.471 |
Coronary artery disease, n (%) | 9 (35) | 11 (30) | 7 (19) | 0.381 |
Heart failure, n (%) | 0 (–) | 3 (8) | 6 (17) | 0.076 |
Hypertension, n (%) | 5 (19) | 9 (24) | 17 (47) | 0.033 |
Diabetes mellitus, n (%) | 2 (8) | 3 (8) | 3 (8) | 0.996 |
Smoking habits, n (%)† | ||||
Current smoker | 16 (67) | 16 (43) | 15 (42) | 0.338 |
Former smoker | 8 (33) | 20 (54) | 20 (56) | |
Never smoker | 0 | 1 (3) | 1 (3) | |
Clinical data | ||||
MAP mm Hg, mean (SD) | 102.1 (13.2) | 100.1 (20.8) | 101.1 (20.0) | 0.613 |
Heart rate per min, mean (SD) | 98.3 (24.4) | 104.3 (19.0) | 95.9 (24.1) | 0.016 |
Atrial fibrillation, n (%) | 0 | 3 (8) | 4 (11) | 0.231 |
Oedema, n (%) | 2 (8) | 8 (22) | 8 (22) | 0.271 |
Chest pain, n (%) | 3 (12) | 14 (15) | 2 (6) | 0.508 |
Chest x-ray, n (%) | ||||
Cephalisation, n (%) | 1 (4) | 7 (21) | 8 (23) | 0.112 |
Infiltrate, n (%) | 1 (4) | 7 (19) | 3 (8) | 0.138 |
Laboratory data | ||||
Haemoglobin g/dl, mean (SD) | 13.9 (1.1) | 13.6 (1.8) | 13.7 (1.8) | 0.853 |
CRP mg/l, median (IQR) | 21 (9–60) | 31 (9–72) | 30 (8–72) | 0.838 |
Leucocytes 109/l, median (IQR) | 9.0 (6.5–12.0) | 11.0 (8.0–16.0) | 10.0 (7.8–14.1) | 0.029 |
Creatinine μmol/l, mean (SD) | 64.4 (16.9) | 70.0 (22.9) | 89.6 (48.1) | <0.001 |
Arterial blood gas, mean (SD) | ||||
pH | 7.41 (0.05) | 7.39 (0.07) | 7.39 (0.11) | 0.414 |
Paco2, kPa, | 5.5 (1.0) | 6.1 (1.3) | 6.3 (2.0) | 0.131 |
Pao2, kPa, | 8.7 (1.5) | 7.9 (1.6) | 8.5 (2.1) | 0.155 |
Sao2, % | 92.5 (3.6) | 88.4 (6.9) | 89.4 (8.1) | 0.038 |
Data from the index admission only.
* In 11 patients we did not have spirometry.
† In two of the patients we did not have data on smoking habits.
BMI, body mass index; CRP, C-reactive protein; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; MAP, mean arterial pressure; Paco2, partial arterial CO2 pressure; Pao2, partial arterial O2 pressure; Sao2, arterial O2 saturation.