Table 1

Outcomes for FVC (% predicted), O₂ saturation postexercise (%) and HRCT for two successive 6 month periods and 1 year based on the International Consensus Statement criteria*

Subject	Baseline	6 months	12 months	Outcomes	Baseline	6 months	12 months	Outcomes	Progression
Subject	FVC	FVC	FVC	By period^†	O₂ Sat	O₂ Sat	O₂ Sat	By period^†	On HRCT
1	49.80	52.50	52.20	S–S–S	75	75	75	S–S–S	None
3	36.70	38.50	41.80	S–S–S	85	78	82	W–I–S	None
4	73.40	70.30	72.70	S–S–S	99	96	97	S–S–S	None
5	59.00	59.80	51.00	S–W–S	61	63	60	I–S–S	Slight^§
8	72.60	69.10	67.40	S–S–S	91	93	92	I–S–S	Slight
11	47.30	37.70	37.40	W–S–W	^‡				^‡
12	66.00	78.80	72.30	I–S–S	83	83	82	S–S–S	None
15	54.00	63.40	56.70	I–W–S	80	74	65	W–W–W	Slight
16	43.10	40.00	40.00	S–S–S	67	82	77	I–W–I	Slight
18	68.30	62.20	59.70	S–S–S	83	82	73	S–W–W	None
19	63.90	59.60	48.10	S–W–W	86	91	86	I–W–S	None
20	49.80	49.50	45.70	S–S–S	85	81	83	W–S–S	None

↵* Stable defined as a value less than a ±10% change for FVC and less than a ±4% point change for O₂ saturation post-exercise. Values at the end of the first period were used as baseline for the second period. One-year outcomes based on ±changes of <19 and 8% for FVC and O₂ saturation, respectively, comparing 12 month values with baseline.
↵† Outcomes are indicated by: I=improved, S=stable and W=worse for the first 6 month period, the second 6 month period and 1 year in that order.
↵‡ Subject unable to perform 6 min walk due to physical disability and baseline HRCT lost.
↵§ Slight progression reflects a change due to a very minimal increase in disease or a technical factor of lung image when comparing 12 month scan with baseline scan.
FVC, forced vital capacity; HRCT, high resolution CT.