Table 1

Patient characteristics at the time of diagnosis of AIPF and comparison with controls with symmetrical IPF

AIPF patients (n=32)Controls (n=64)p Value
Mean±SD age (years)69±763±120.020
M/F, n (%)26 (81.2)/6 (18.8)47 (73.4)/17 (26.6)0.554
Non/ex/current smokers, n (%)9 (28.1)/21 (66.6)/2 (6.2)21 (32.8)/35 (54.7)/8 (12.5)0.500
Gastro-oesophageal reflux, n (%)20 (62.5)20 (31.3)0.006
Mean±SD BMI (kg/m2)26±3.826±3.80.710
NYHA class I–II/III–IV, n (%)23 (71.9)/9 (28.1)38 (59.5)/26 (40.6)0.330
Digital clubbing, n (%)8 (25)29 (45.3)0.088
Functional parameters
 FEV1 (% pred)76±2176±180.890
 FVC (% pred)70±2073±180.430
 TLC (% pred)67±2272±150.120
 Tlco (% pred)52±1943±130.009
 Pao2 (mm Hg)73±1377±20.120
  • AIPF, asymmetrical idiopathic pulmonary fibrosis; BMI, body mass index; % pred, percentage of predicted value; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; NYHA, New York Heart Association; Pao2, room air arterial oxygen tension; TLC, total lung capacity; Tlco, carbon monoxide transfer factor.