Patient characteristics at the time of diagnosis of AIPF and comparison with controls with symmetrical IPF
| AIPF patients (n=32) | Controls (n=64) | p Value | |
| Mean±SD age (years) | 69±7 | 63±12 | 0.020 |
| M/F, n (%) | 26 (81.2)/6 (18.8) | 47 (73.4)/17 (26.6) | 0.554 |
| Non/ex/current smokers, n (%) | 9 (28.1)/21 (66.6)/2 (6.2) | 21 (32.8)/35 (54.7)/8 (12.5) | 0.500 |
| Gastro-oesophageal reflux, n (%) | 20 (62.5) | 20 (31.3) | 0.006 |
| Mean±SD BMI (kg/m2) | 26±3.8 | 26±3.8 | 0.710 |
| NYHA class I–II/III–IV, n (%) | 23 (71.9)/9 (28.1) | 38 (59.5)/26 (40.6) | 0.330 |
| Digital clubbing, n (%) | 8 (25) | 29 (45.3) | 0.088 |
| Functional parameters | |||
| FEV1 (% pred) | 76±21 | 76±18 | 0.890 |
| FVC (% pred) | 70±20 | 73±18 | 0.430 |
| TLC (% pred) | 67±22 | 72±15 | 0.120 |
| Tlco (% pred) | 52±19 | 43±13 | 0.009 |
| Pao2 (mm Hg) | 73±13 | 77±2 | 0.120 |
AIPF, asymmetrical idiopathic pulmonary fibrosis; BMI, body mass index; % pred, percentage of predicted value; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; NYHA, New York Heart Association; Pao2, room air arterial oxygen tension; TLC, total lung capacity; Tlco, carbon monoxide transfer factor.