Table 1

Summary of outcomes by study arm

OutcomeStudy armPrevalence ratio (95% CI)p Value
12-monthly6-monthly
N (%)N (%)
Primary outcomes
 Proportion of TB cases detected by radiological screening179/632 (28.3)197/670 (29.4)1.04 (0.88 to 1.23)0.67
 Proportion sputum smear-positive of those culture-positive for Mtb291/346 (84.1)334/390 (85.6)1.02 (0.96 to 1.08)0.56
Secondary outcomes
 Radiological extent of disease (n)84 (100)106 (100)
  Number of zones
   0–128 (33)28 (26)N/A0.05
   2–323 (27)47 (44)
   4–633 (39)31 (29)
RateN/pyrs*RateN/pyrs*HR (95% CI)
Mortality
 All-cause mortality12.6269/21.311.7248/21.20.92 (0.78 to 1.10)0.4
 TB-specific mortality2.860/21.32.144/21.20.73 (0.50 to 1.08)0.1
 TB-specific mortality within first 2 months1.123/21.30.5211/21.20.48 (0.23 to 0.98)0.04
TB incidence
 Overall30.3632/20.932.2670/20.81.06 (0.95 to 1.18)0.3
  • * per 1000 person-years (pyrs).

  • TB, tuberculosis; Mtb, Mycobacterium tuberculosis.