Table 3

Single nucleotide polymorphism (SNP) associations with bronchiectasis in α1-antitrypsin deficiency

Genotype model (p)Allele model (p)Allele OR95% CI
rs2070741 [A/C]0.0310.0461.801.02 to 3.19
rs2298849 [C/T]0.0130.221
rs4588 [C/A]0.2800.067
rs7041 [G/T]0.5260.0270.520.29 to 0.93
  • The table shows the p values and OR and 95% CI of bronchiectasis for each SNP; in each case the OR was computed for the minor allele. All results with p<0.1 are shown. No OR has been computed for rs2298849 and rs4588 since the allele analyses were non-significant.